(website under construction)
Welcome to the Timmons laboratory home page. We are in the Department of Molecular Biosciences at the University of Kansas in Lawrence, Kansas. We study conserved RNA interference and related epigenetic mechanisms. Our experiments commonly employ the Caenorhabditis elegans model genetics system due to the wealth of molecular, cellular, and biochemical tools that are available. We are particularly interested in elucidating the mechanisms that connect environmental conditions and diet to epigenetic mechanisms that affect gene expression and chromatin functions.
Discovery and impact of RNAi (NOVA video, 15min) Gene expression and RNAi mechanisms (Nature video, 5min) Small non-coding RNA and gene expression (NatureEducation, text) RNAi flash animation (Sirna Therapeutics, 1min) RNAi flash animation (Nature Reviews Genetics) The Ghost in your Genes (Epigenetics and health, Discovery/Science, 49min) Epigenetics (Begin before birth video, 4min) Epigenetic Mechanisms (Cell Signaling Technology, 2min)